Spinach Artichoke Chicken Casserole Recipe
This Spinach Artichoke Chicken Casserole recipe is an easy make-ahead meal the whole family will love. This is your favorite spinach and artichoke dip turned into a creamy, cheesy chicken casserole recipe.
Spinach and artichoke is one of my favorite flavor combinations. I adore spinach dip. Add some protein, and it becomes dinner! It pairs perfectly with chicken for an easy casserole.
This is great for meal prepping because you can prep it a day or two before and just pop it in the oven for about half an hour before serving. This casserole is pure comfort food.
Make sure to try my Spinach & Artichoke Stuffed Chicken Breasts and Lazy Spinach Artichoke Chicken Breasts for more simple dinners. Or make my Keto Spinach Artichoke Dip Bites for the perfect app!
Ingredients
- Chicken – You can use any type of cooked chicken. Chicken breasts, chicken thighs, or rotisserie chicken. Casseroles are a great way to use up leftover chicken.
- Spinach – I used fresh baby spinach but frozen spinach that has been thawed and drained is fine too.
- Artichoke Hearts – Canned artichoke hearts, a jar of marinated artichoke hearts that have been drained, or thawed frozen artichoke hearts all work.
- Cream Cheese, Sour Cream, & Mayo – This creamy combo is my trifecta for a perfect casserole. I use all three in almost every casserole I make.
- Provolone Cheese – Slices of provolone cheese cover the top perfectly but you can use the shredded cheese of your choice if you prefer.
- Seasoning – I use a combo of onion, garlic, thyme, and kosher salt.
See quantities in the recipe card.
How to Make Spinach & Artichoke Chicken Casserole
1️⃣ Make the Filling
Combine all the ingredients (besides the slices of cheese) in a large bowl and stir well. Adjust the seasonings to taste.
👉 Tip: Using room temperature ingredients makes it easier to mix.
2️⃣ Assembly
Put the chicken and spinach mixture into a large baking dish. Any casserole dish about 9 x 13 will work. Stop with the cheese slices.
3️⃣ Bake the Casserole
Put the pan in a preheated oven. Bake the chicken spinach artichoke casserole until hot. Enjoy!
Storage
Store leftovers in the fridge for 3-4 days in an airtight container. To reheat, I usually microwave individual portions. If you have an entire casserole you want to reheat, bake it covered with aluminum foil.
Variations
- Cheese – Feel free to top this casserole with any mild cheese. Mozzarella cheese or grated parmesan cheese works really well too!
- Bacon- Add in some cooked chopped bacon crumbles for a boost of flavor.
- Spicy – Crushed red pepper adds a nice zing. Black pepper can also add some extra flavor.
Make sure to try this Creamy Chicken Piccata Casserole Recipe next!
Common Questions
Can I use frozen spinach?
Yes. I used fresh spinach in this one so I didn’t have to thaw and drain frozen spinach. It worked really well. I was afraid the liquid released from the spinach would add too much liquid to the sauce. But it didn’t.
But, if you prefer to use frozen spinach just thaw and drain it first.
How do I serve a chicken casserole?
Many traditional chicken casseroles call for pasta or rice. To keep this low carb we avoid adding those. I normally serve with a side of green vegetables or a garden salad. You can also serve it on top of cauliflower rice, hearts of palm noodles, or spaghetti squash.
Why is my casserole watery and how can I thicken it?
The best way to fix a watery casserole is to prevent it from happening! This is the reason to use cooked chicken instead of raw when making a casserole. Raw chicken releases liquid as it cooks which makes your casserole thin.
If you end up with a watery casserole anyway you can sprinkle a little xanthan gum or glucomannan into the sauce to thicken it.
Try this Keto Philly Cheesesteak Chicken Casserole next! Or for a vegetable based option my Leftover Broccoli Casserole Recipe is perfect!
Want to Save This Recipe?
Enter your email below & we’ll send it to your inbox. Plus get great new recipes from us every week!
By submitting this form, you consent to receive emails from Joy Filled Eats
Spinach Artichoke Chicken Casserole
Ingredients
- 4 oz cream cheese softened
- 1/2 cup sour cream
- 1/2 cup mayo
- 2 tbsp dried minced onion
- 1 tbsp garlic powder
- 1 tsp thyme
- 1 tsp salt
- 2 pound cooked chicken breast cubed
- 1 cup chopped marinated artichokes drained
- 4 oz fresh spinach (2 big handfuls)
- 10 slices provolone cheese divided (about 7.5 oz) (or use shredded)
Instructions
- Preheat the oven to 400.
- In a large mixing bowl stir together the cream cheese, sour cream, mayo, and seasonings until smooth. Mix in the chicken, artichokes, and spinach. Cut 4 of the slices of provolone into pieces and stir those in.
- Spread in the bottom of a large 10 x 13 inch casserole dish. Top with the additional 6 slices of cheese.
- Bake for 25 – 35 minutes until golden, hot, and bubbly. Serve with green veggies or a salad.
Nutrition
Like what you see? Follow me on Facebook and Instagram! Love this recipe? Leave a comment & a 5-star rating right here! Make sure you don’t miss new recipes by getting email updates!
Originally Published March 4, 2017. Revised and Republished December 5, 2025.
I enjoyed this recipe but thought the tablespoon of garlic might be a misprint? Is that correct?
Thanks.
It is not. If you don’t love garlic you are welcome to cut back but we like the flavor using a full tablespoon.
I am looking SO forward to having this tonight! First time trying this!
My family loved this, my granddaughter wanted to take left overs to school for lunch! It’s going to be a regular.
Thank you! for this DELICIOUS recipe. I’m definitely going to keep this recipe in my dinner rotation.
I ended up with a very watery sauce in the pan. It was not thick like the picture. I had to add about four handfuls of shredded cheese to thicken it to serve as a sauce for the family over noodles.
It seems like your spinach may have released more liquid than usual. You could saute it first next time.
Ok, this was AMAZING – especially for how EASY it was to put together.
I subbed a Swiss / Gruyère shredded mix & I added water chestnuts (because they are one of my favorite parts of spinach artichoke dip). I even used canned chicken and couldn’t tell it was canned (I don’t like canned chicken but there was so much flavor in this recipe, that it worked!) My 9 year old twins even loved it. Thank you for the great simple recipe for a busy working mom living the keto life.
Could I sub mozzarella for the provolone?
Sure!
LOVE LOVE SPINACH ❣️. THANK YOU SO MUCH ; AWESOME RECIPES ❣️😋
So delicious, go to casserole. Thank you for posting.
I was on my way to making this for dinner, and I’m wondering What kind of artichokes you use? The kind I have has a lot of carbs. I’m just starting out on Keto, so I’m checking everything and looking for suggestions. Thanks for your help.
They also have fiber, and they have a pretty potent flavor so a little goes a long way. I normally use the canned in water type but the ones jarred in oil can work too.
Absolutely delicious, my whole family loved it!